What are three types of osteogenic sarcoma?
Telangiectatic osteosarcoma. Intraosseous well-differentiated or low-grade central osteosarcoma. Small cell osteosarcoma.
What is the meaning of osteogenic sarcoma?
(OS-tee-oh-JEH-nik sar-KOH-muh) A cancer of the bone that usually affects the large bones of the arm or leg. It occurs most commonly in young people and affects more males than females.
What are the causes of osteosarcoma?
What causes osteosarcoma? The exact cause of osteosarcoma is not known, but it is believed to be due to DNA mutations inside bone cells—either inherited or acquired after birth.
Where is the osteogenic sarcoma?
Osteosarcoma is a type of bone cancer that begins in the cells that form bones. Osteosarcoma is most often found in the long bones — more often the legs, but sometimes the arms — but it can start in any bone. In very rare instances, it occurs in soft tissue outside the bone.
How osteosarcoma is diagnosed?
A bone scan is a way to find out whether or not osteosarcoma may have spread to other bones beyond the place it started. Biopsy. A biopsy is the removal of a small amount of tissue for examination under a microscope. Other tests can suggest that a tumor is present, but only a biopsy can make a definitive diagnosis.
How is osteosarcoma diagnosed?
What is Stage 3 osteosarcoma?
In summary: Low-grade, localized tumors are stage I. High-grade, localized tumors are stage II. Metastatic tumors (regardless of grade) are stage III.
What are the complications of osteosarcoma?
Osteosarcoma and its treatment can lead to complications including:
- Bone fractures.
- Wound infection and slow healing.
- Problems with a donor bone graft or prosthesis.
- Chemotherapy side effects such as anemia, bleeding, kidney or liver damage, hearing loss, and a higher risk of other cancers.
What is osteogenic sarcoma?
Osteogenic sarcoma Definition and diagnostic criteria Osteosarcoma is a primary malignant tumour of the skeleton characterised by the direct formation of immature bone or osteoid tissue by the tumour cells. More rarely osteosarcoma may arise in the soft tissue.
What is the pathophysiology of osteosarcoma?
Osteosarcoma (OS) is a skeletal tumor affecting mainly children and adolescents. The presence of distance metastasis is frequent and it is localized preferentially to the lung, representing the main reason for death among patients. The therapeutic approaches are based on surgery and chemotherapeutics.
Can X-rays cause osteogenic sarcoma?
With X-rays, however, 500 rads delivered to the endosteal surface of a mouse femur has been shown to cause osteogenic sarcoma. Bone tumors can be induced in mice by viruses. FBJ osteosarcoma virus and RFB osteoma virus were obtained from spontaneous tumors; FBR osteosarcoma virus came from a radiation-induced tumor.
What are the signs and symptoms of osteosarcoma?
Although about 90% of osteosarcoma show soft tissue extension, a few patients complain of swelling. Systemic symptoms as weight loss, pallor, fever, anorexia are very uncommon. Go to: Etiology Etiology of osteosarcoma is unknown.